Predicting Success in Quitting Smoking

Categories: Event at ORI

Type: Event at ORI

Date Published: 09/22/2014

ABOUT THIS TALK: A small subcontract we received at SRI International in 1998 started us on this road. I was just completing a study of tobacco dependence in smokeless tobacco users and had found it easy and accurate to administer the required questionnaires and tests on a laptop computer, rather than in paper-pencil form. Through the subcontract from the University of Michigan, our group was tasked with developing a questionnaire that could be used to study tobacco use across the lifespan, as a way to study smoking phenotypes. We broadened the scope from smoking to any tobacco use, obtained free web-survey programming and web sample, and developed the Lifetime Tobacco Use Questionnaire (LTUQ) as a web-based tool. Working with ORI and the University of Pittsburgh, we adapted and used the LTUQ to study the validity of tobacco-use self-reporting, as part of a multi-year project funded by the National Institutes of Health. Based on the results from the LTUQ, NIH's National Cancer Institute contracted with us to develop the Recent Tobacco Use Questionnaire (RTUQ), which used the same techniques to study current tobacco use and provide stop-smoking recommendations. We then moved from web-based surveys and interventions to the mobile space of mHealth. Drawing on data from thousands of patients previously enrolled in stop-smoking studies at SRI, we developed an algorithm for predicting success in quitting based on outcome data from the clinical trials. The results of the algorithm analyses became the basis for stop-smoking app content for mobile devices. This presentation follows the events and conclusions from the beginnings of the LTUQ in 1998 to recent efforts and future plans to apply the findings in new ways. Dr. Brigham's colloquium is September 23 at 3:00 p.m. in the Wolf Conference Room at ORI.

As a researcher at SRI International in Menlo Park, CA, Janet Brigham, Ph.D., was the principal architect of a stop-smoking app (Free2Quit), as well as two survey projects funded by the National Institutes of Health: the Lifetime Tobacco Use Questionnaire (LTUQ) and the Recent Tobacco Use Questionnaire (RTUQ), both Web-based instruments designed to assess tobacco use. The RTUQ also provided stop-smoking treatment and self-help recommendations.

An experimental psychologist with a Ph.D. from Brigham Young University, Dr. Brigham received postdoctoral training and worked in fellowship positions at the Johns Hopkins University School of Medicine Behavioral Pharmacology Research Unit, the National Institute on Drug Abuse Addiction Research Center, and the University of Pittsburgh School of Medicine’s Western Psychiatric Institute and Clinic. Additionally, she served as a full-time consultant to the World Health Organization’s Tobacco Free Initiative. Her research work has explored the factors that lead to and sustain tobacco use, as well as determining efficacious ways to study tobacco use across the lifespan. Other interests include psychometrics and risk factors; epigenetics and genealogy; and the history of mental health treatment.