EPINET is a national learning health care system for early psychosis. EPINET links early psychosis clinics through standard clinical measures, uniform data collection methods, data sharing agreements, and integration of client-level data across service users and clinics. Clients and their families, clinicians, health care administrators, and scientific experts partner within EPINET to improve early psychosis care and conduct large-scale, practice-based research.

ESPRITO is a hub within the EPINET project that connects 12 clinics. In addition to the learning health system, the team is conducting two sub-studies that address core clinical issues for improving care. The first of these examines premature patient disengagement, a crucial clinical problem as patients who leave treatment early do not get the full benefit of the program. The second examines whether natural language processing can provide additional data beyond usual clinical measures.